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First-in-human trial to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of STR-324, a dual enkephalinase inhibitor for pain management.

Laurence M MossCécile L BerendsEmilie M J van BrummelenIngrid M C KamerlingErica S KlaassenKirsten BergmannVanessa VilleVictor Juarez-PerezAnnie-Claude BenichouGeert Jan Groeneveld
Published in: British journal of clinical pharmacology (2021)
EudraCT (2014-002402-21) and toetsingonline.nl (63085).
Keyphrases
  • pain management
  • endothelial cells
  • chronic pain
  • open label
  • phase iii
  • study protocol
  • clinical trial
  • phase ii
  • induced pluripotent stem cells
  • pluripotent stem cells
  • double blind