Prospective evaluation of minimal residual disease monitoring to predict prognosis of adult patients with Ph-negative acute lymphoblastic leukemia.
Koji NagafujiToshihiro MiyamotoTetsuya EtoRyosuke OgawaHirokazu OkumuraKen TakaseNoriaki KawanoYasuhiko MiyazakiTomoaki FujisakiAtsushi WakeYuju OhnoToshiro KurokawaTomohiko KamimuraYasushi TakamatsuShouhei YokotaKoichi AkashiPublished in: European journal of haematology (2019)
These results indicate that DFS of about 70% can be expected in MRD-negative patients after induction therapy, and the patients did not benefit from HSCT in 1CR. This study was registered with the UMIN Clinical Trials Registry (UMIN-CTR), number UMIN000001519.