Genetic spectrum of Kallmann syndrome: Single-center experience and systematic review.

Virendra A PatilAnurag Ranjan LilaNalini ShahSneha AryaVijaya SarathiRavikumar Shah Swati S JadhavSaba Samad MemonManjiri KarlekarTushar R Bandgar

Published in: Clinical endocrinology (2022)

This systematic review highlights that the genetic yield is 31% in KS probands, with distinct regional variations. The association of severe reproductive phenotype with the higher genetic yield needs further validation.

Keyphrases

systematic review
meta analyses
genome wide
randomized controlled trial
early onset
gene expression