Polypharmacy and antidepressant acceptability in comorbid depression and type 2 diabetes: a cohort study using UK primary care data.
Annie JefferyCini BhanuKate R WaltersIan Chi Kei Ck WongDavid P J OsbornJoseph F HayesPublished in: The British journal of general practice : the journal of the Royal College of General Practitioners (2023)
Early discontinuation of antidepressants is common in adults with T2DM; however, individuals with higher levels of concurrent polypharmacy may be more adherent to treatment. These are likely to represent individuals with worse physical or mental health. Individuals with lower levels of concurrent polypharmacy may benefit from adherence support.
Keyphrases
- mental health
- primary care
- type diabetes
- major depressive disorder
- glycemic control
- adverse drug
- cardiovascular disease
- locally advanced
- depressive symptoms
- physical activity
- electronic health record
- mental illness
- squamous cell carcinoma
- emergency department
- big data
- insulin resistance
- cross sectional
- adipose tissue
- metabolic syndrome
- sleep quality
- deep learning
- smoking cessation