Unveiling difficult-to-treat rheumatoid arthritis: long-term impact of biologic or targeted synthetic DMARDs from the KOBIO registry.
Ju-Yang JungEunyoung LeeJi-Won KimChang-Hee SuhKichul ShinJinhyun KimWook-Young BaekPublished in: Arthritis research & therapy (2023)
D2T RA patients experienced higher disease activity despite maintaining b/tsDMARD therapy. Withdrawal rates due to inefficacy were higher in D2T RA. Effective therapeutic strategies are needed to improve disease control and treatment outcomes in this unique patient population.
Keyphrases
- rheumatoid arthritis
- disease activity
- rheumatoid arthritis patients
- ankylosing spondylitis
- systemic lupus erythematosus
- end stage renal disease
- interstitial lung disease
- juvenile idiopathic arthritis
- chronic kidney disease
- newly diagnosed
- peritoneal dialysis
- prognostic factors
- stem cells
- cancer therapy
- patient reported outcomes
- smoking cessation
- cell therapy
- systemic sclerosis
- bone marrow
- drug delivery