Safety of treating acute pulmonary embolism at home: an individual patient data meta-analysis.
Dieuwke LuijtenDelphine DouilletKim LuijkenCécile TromeurAndrea PenalozaOlivier HugliDrahomir AujeskyAlexandru GrigoreanJoseph R BledsoeKyle E ChangFrancis CouturaudPaul L den ExterCarme FontMenno V HuismanDavid JimenezChristopher KabrhelJeffrey A KlineStavros V KonstantinidesThijs E van MensRemedios OteroW Frank PeacockOlivier SanchezWilliam B StubblefieldLuca ValerioDavid R VinsonPhilip WellsMaarten van SmedenPierre-Marie RoyFrederikus Albertus KlokPublished in: European heart journal (2024)
The incidence of adverse events in home-treated PE patients, selected by a validated triage tool, was very low. Patients with cancer had a three- to five-fold higher incidence of adverse events and death. Patients with increased troponin or (NT-pro)BNP had a three-fold higher risk of adverse events, driven by recurrent venous thromboembolism and bleeding.
Keyphrases
- pulmonary embolism
- venous thromboembolism
- systematic review
- end stage renal disease
- newly diagnosed
- risk factors
- emergency department
- inferior vena cava
- ejection fraction
- chronic kidney disease
- healthcare
- liver failure
- peritoneal dialysis
- prognostic factors
- randomized controlled trial
- direct oral anticoagulants
- meta analyses
- machine learning
- intensive care unit
- hepatitis b virus
- aortic dissection