An open-label pilot study of oral vitamin C as an opioid-sparing agent in patients with chronic pain secondary to cancer.
E PinkertonP GoodK GibbonsJanet Rea HardyPublished in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2016)
This study failed to demonstrate any clinically significant benefit from vitamin C in conjunction with opioids in cancer-related pain and does not provide support for embarking on a larger randomised trial to determine efficacy.