Human parvovirus B19 infection in malignant and benign tissue specimens of different head and neck anatomical subsites.

Haniyeh AbueiSepide NamdariTahereh PakdelFatemeh PakdelAzadeh Andishe-TadbirAbbas Behzad-BehbahaniMohammad J AshrafParnian AlaviAli Farhadi

Published in: Infectious agents and cancer (2023)

To sum up, B19V was frequently present in HNSCC tissues of Iranian patients but mostly absent in the adjacent non-tumor tissues as well as oral mucocele lesions, buccal, and nasopharyngeal swabs of healthy subjects. HPV possibly contributes to B19V persistence in HNSCC tissues. Additional research is required to investigate potential etiological or cofactor roles of B19V in the development of HNSCCs.

Keyphrases

gene expression
end stage renal disease
newly diagnosed
endothelial cells
ejection fraction
chronic kidney disease
high grade
patient reported outcomes
risk assessment
pluripotent stem cells
patient reported