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Evaluation of the Expression of Infection-Related Long Noncoding RNAs among COVID-19 Patients: A Case-Control Study.

Zahra FirooziElham MohammadisoleimaniFarzaneh BagheriAtefeh TaheriBabak PezeshkiMohammad Mehdi NaghizadehAbdolreza DaraeiJalal KarimiYousef GholampourYaser MansooriZahra Montaseri
Published in: Genetics research (2024)
The considerable higher expression of ISR, ATV, and HEAL lncRNAs and the significant area under curve (AUC) in ROC curve demonstrate that these RNAs probably have a potential role in controlling the host innate immune responses and regulate the viral replication of SARS-CoV-2. However, these assumptions need further in vitro and in vivo investigations to be confirmed.
Keyphrases
  • sars cov
  • immune response
  • poor prognosis
  • respiratory syndrome coronavirus
  • binding protein
  • dendritic cells
  • transcription factor
  • inflammatory response
  • coronavirus disease
  • drug induced