Increasing the sensitivity of hyperpolarized [15 N2 ]urea detection by serial transfer of polarization to spin-coupled protons.

Felix KreisAlan J WrightVencel SomaiRachel Katz-BrullKevin M Brindle

Published in: Magnetic resonance in medicine (2020)

The sequence gave an SNR increase that was close to the theoretical limit and can give a significant SNR benefit when compared to direct 13 C detection of hyperpolarized [13 C]urea.

Keyphrases

loop mediated isothermal amplification
label free
room temperature
molecular dynamics
sensitive detection
amino acid