Genetic European Ancestry and Incident Diabetes in Black Individuals: Insights From the SPRINT Trial.
Vibhu ParchaBrittain F HeindlRajat KalraAdam P BressShreya RaoAmbarish PandeyBarbara A GowerMarguerite R IrvinMerry-Lynn N McDonaldTanja DudenbostelGarima AroraPankaj AroraPublished in: Circulation. Genomic and precision medicine (2022)
The higher risk of incident diabetes in Black individuals may have genetic determinants in addition to adverse social factors. Further research may help understand the interplay between biological and social determinants of cardiometabolic health in Black individuals. Registration: URL: https://www.clinicaltrials.gov; Unique identifier: NCT01206062.
Keyphrases
- cardiovascular disease
- type diabetes
- healthcare
- mental health
- glycemic control
- genome wide
- public health
- clinical trial
- copy number
- study protocol
- gene expression
- randomized controlled trial
- phase ii
- health information
- dna methylation
- metabolic syndrome
- risk assessment
- adipose tissue
- open label
- climate change
- genome wide association study