PD-1 expression affects cytokine production by ILC2 and is influenced by peroxisome proliferator-activated receptor-γ.
Banu BatyrovaFien LuwaertPanagiota MaraveliaYuria MiyabayashiNeha VashistJulian M StarkSara Y SooriChristopher Andrew TibbittPeggy RieseJonathan M CoquetBenedict J ChambersPublished in: Immunity, inflammation and disease (2019)
These findings illustrate that chronic loss of PD-1 plays a role in ILC2 function and PD-1 expression can be modulated by PPAR-γ.