Retinoic acid-related orphan receptor C isoform 2 expression and its prognostic significance for non-small cell lung cancer.

Qi HuangJinshuo FanXin QianZhilei LvXiuxiu ZhangJieli HanFeng WuCaiyun ChenJiao DuMengfei GuoGuorong HuYang Jin

Published in: Journal of cancer research and clinical oncology (2015)

Our study suggests that RORC2 is expressed by lung cancer cells and greatly contributes to tumour cell proliferation and overall survival in NSCLC. These findings strongly imply that RORC2 is associated with tumour progression.

Keyphrases

cell proliferation
small cell lung cancer
poor prognosis
cell cycle
advanced non small cell lung cancer
pi k akt
signaling pathway