The effectiveness of high-intensity interval training on body composition of rodent models of obesity: A systematic review and meta-analysis.
Ana Flávia SordiBruno Ferrari SilvaJulia Pedrosa FurlanSolange Marta Franzói de MoraesDébora Alves GuarigliaSidney Barnabé PeresPublished in: Physiology international (2022)
The present systematic review was compiled to analyze the effectiveness of High-intensity interval training (HIIT) protocols on the body composition of rodents with obesity. Databases were searched until February 2021 for experimental trials in rodents with a minimum duration of four weeks of HIIT and endpoints associated with obesity. The data were analyzed by meta-analysis performed for comparisons of body composition. Sensitivity analysis was performed to investigate the consistency of individual researches. Of all of the 524 studies found, only 14 were included. The analysis showed a significant reduction in body weight ([CI 95%: -8.35; -1.98] P ≤ 0.01), adiposity index ([IC 95%: -1.04; -0.80] P ≤ 0.01), and fat pads ([IC 95%: -0.59; -0.06] P ≤ 0.01). HIIT performed on treadmill or water was effective to reduce body weight (P < 0.05). In conclusion, HIIT attenuated both body weight and adiposity induced either by HFD (high-fat diet) or by GOM (genetic obese model), thereby inducing positive changes in body composition.
Keyphrases
- body composition
- body weight
- insulin resistance
- high fat diet
- systematic review
- adipose tissue
- metabolic syndrome
- resistance training
- weight loss
- high intensity
- bone mineral density
- high fat diet induced
- type diabetes
- meta analyses
- weight gain
- skeletal muscle
- randomized controlled trial
- bariatric surgery
- big data
- dna methylation
- gene expression
- oxidative stress
- high glucose
- diabetic rats
- body mass index
- endothelial cells
- physical activity
- gestational age
- postmenopausal women
- artificial intelligence
- obese patients
- deep learning