Glucagon-like peptide-1 receptor agonists and risk of bone fracture in patients with type 2 diabetes: A meta-analysis of randomized controlled trials.

Liang ChengYun HuYun-Yun LiXin CaoNing BaiTing-Ting LuGuo-Qing LiNa LiAn-Ning WangXiao-Ming Mao

Published in: Diabetes/metabolism research and reviews (2019)

Compared with placebo and other anti-diabetic drugs, liraglutide and lixisenatide were associated with a significant reduction in the risk of bone fractures, and the beneficial effects were dependent on the duration of treatment.

Keyphrases

bone mineral density
soft tissue
systematic review
bone loss
bone regeneration
postmenopausal women
randomized controlled trial
combination therapy
body composition