Testosterone Treatment, Weight Loss, and Health-related Quality of Life and Psychosocial Function in Men: A 2-year Randomized Controlled Trial.
Mathis GrossmannKristy P RobledoMark DanielDavid J HandelsmanWarrick J InderBronwyn G A StuckeyBu B YeapMark Ng Tang FuiKaren BrackenCarolyn A AllanDavid JesudasonJeffrey D ZajacGary Allen WittertPublished in: The Journal of clinical endocrinology and metabolism (2024)
In this diabetes prevention trial, weight loss induced by a lifestyle intervention improved HR-QOL and psychosocial function in more domains than testosterone treatment. The magnitude of weight and waist circumference reduction were predicted by baseline physical function, depressive symptomology, and sense of coherence.