End-stage renal disease reduces the expression of drug-metabolizing cytochrome P450s.
Máté Tamás DériÁdám Ferenc KissKatalin TóthJózsef PaulikEnikő SárváryLászló KóboriKatalin MonostoryPublished in: Pharmacological reports : PR (2020)
Reduced CYP expression was a direct evidence of transcriptional down-regulation of CYP genes in patients with impaired kidney function.