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Advancement of Research Progress on Synthesis Mechanism of Cannabidiol (CBD).

Fu WangZhenyuan ZangQian ZhaoChunxiao XiaoyangXiujuan LeiYingping WangYiqiao MaRongan CaoXixia SongLili TangMichael K DeyholosJian Zhang
Published in: ACS synthetic biology (2024)
Cannabis sativa L. is a multipurpose crop with high value for food, textiles, and other industries. Its secondary metabolites, including cannabidiol (CBD), have potential for broad application in medicine. With the CBD market expanding, traditional production may not be sufficient. Here we review the potential for the production of CBD using biotechnology. We describe the chemical and biological synthesis of cannabinoids, the associated enzymes, and the application of metabolic engineering, synthetic biology, and heterologous expression to increasing production of CBD.
Keyphrases
  • human health
  • poor prognosis
  • ms ms
  • health insurance
  • risk assessment
  • saccharomyces cerevisiae