Effects of prednisolone tapering on effectiveness of infliximab in patients with ulcerative colitis: data from a retrospective cohort.

Pernille Dige OvesenMohamed AttauabiJohan F K F IlvemarkMads Damsgaard WewerDavid J WarrenJohan BurischRolf A KlaasenNils BolstadCasper SteenholdtJakob Benedict Seidelin

Published in: BMJ open gastroenterology (2024)

In UC patients with limited disease burden, prednisolone did not affect effectiveness of infliximab. However, patients with increased disease burden seem to benefit from corticosteroid combination therapy.

Keyphrases

ulcerative colitis
combination therapy
randomized controlled trial
systematic review
electronic health record
risk factors