HIV-associated opsoclonus-myoclonus-ataxia syndrome: early infection, immune reconstitution syndrome or secondary to other diseases? Case report and literature review.
Bruno Fukelmann GuedesMárcio A A Vieira FilhoClarice ListikRafael B CarraCristiane B PereiraEmanuelle Roberta da Silva AquinoHélio R GomesJosé E VidalPublished in: Journal of neurovirology (2017)
Opsoclonus-myoclonus-ataxia (OMA) syndrome is a debilitating autoimmune neurological disorder. Post-infectious opsoclonus-myoclonus-ataxia syndrome has been described with varying bacterial, spirochetal, and viral infections including several patients with HIV. However, specific immunopathological mechanisms that may lead to opsoclonus-myoclonus in HIV-positive patients are unknown.We report a case of HIV-associated opsoclonus-myoclonus and early HIV infection. A review of published literature shows opsoclonus-myoclonus can occur during early infection, in immune reconstitution syndrome or in association with other infections, especially tuberculosis.
Keyphrases
- hiv positive
- antiretroviral therapy
- men who have sex with men
- human immunodeficiency virus
- hiv infected
- hiv testing
- hiv aids
- case report
- south africa
- hepatitis c virus
- early onset
- systematic review
- ejection fraction
- newly diagnosed
- prognostic factors
- sars cov
- randomized controlled trial
- drug induced
- cerebral ischemia