Ecdysoneless Overexpression Drives Mammary Tumorigenesis through Upregulation of C-MYC and Glucose Metabolism.

Bhopal C MohapatraSameer MirzaAditya BeleChannabasavaiah Basavaraju GurumurthyMohsin RazaIrfana SaleemMatthew D Storck Aniruddha SarkarSai Sundeep KollalaSurendra K ShuklaSiddesh Southekal Kay-Uwe WagnerFang QiuSubodh M LeleMansour A AlsaleemEmad A RakhaChittibabu GudaPankaj K SinghRobert D Cardiff Hamid Band Vimla Band

Published in: Molecular cancer research : MCR (2022)

We demonstrate ECD overexpression in the mammary gland of mice led to the development of a tumor progression model through upregulation of c-MYC signaling and glucose metabolism.

Keyphrases

cell proliferation
poor prognosis
long non coding rna
transcription factor
signaling pathway
high fat diet induced
insulin resistance
light emitting