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Drug-induced oral lichenoid reactions: a real clinical entity? A systematic review.

Giulio FortunaMassimo AriaJulie H Schiavo
Published in: European journal of clinical pharmacology (2017)
This systematic review demonstrated that there is no strong scientific evidence to support the causal relationship between any drug and oral lichenoid lesions; therefore, in all reviewed cases, we must question whether the DIOLRs represent a real and separate clinical entity. Further and more thorough investigations using one of the available algorithms for adverse drug reaction are warranted.
Keyphrases
  • adverse drug
  • drug induced
  • liver injury
  • systematic review
  • machine learning
  • electronic health record
  • randomized controlled trial
  • meta analyses
  • deep learning