Enhanced Visualization of Subtle Outer Retinal Pathology by En Face Optical Coherence Tomography and Correlation with Multi-Modal Imaging.

Danuta M SampsonDavid Alonso-CaneiroAvenell L ChewTina LameyTerri McLarenJohn De RoachFred K Chen

Published in: PloS one (2016)

Graph-search theory algorithm helps to overcome the limitations of outer retinal segmentation inaccuracies in commercial software. En face OCT images can provide detailed topography of the reflectivity within a specific layer of the retina which correlates with other forms of fundus imaging. Our results highlight the need for standardization of image reflectivity to facilitate quantification of en face OCT images and longitudinal analysis.

Keyphrases

optical coherence tomography
diabetic retinopathy
deep learning
optic nerve
convolutional neural network
high resolution
machine learning
neural network
photodynamic therapy
cross sectional
electron microscopy