The role of FGF-4 and FGFR-2 on preimplantation embryo development in experimental maternal diabetes.

Filiz Yilmaz Serap Cilaker Micili Guven Erbil

Published in: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology (2021)

We concluded that FGF-4 and FGFR-2 overexpression might impair mouse pre-implantation embryo development in maternal diabetes and suggest investigating whether they have crucial effects on human embryo development and infertility in maternal diabetes.

Keyphrases

pregnancy outcomes
type diabetes
cardiovascular disease
glycemic control
birth weight
endothelial cells
pregnant women
cell proliferation
physical activity
adipose tissue
metabolic syndrome
skeletal muscle
gestational age
induced pluripotent stem cells
weight gain
pluripotent stem cells