Clinically relevant sequence types of carbapenemase-producing Escherichia coli and Klebsiella pneumoniae detected in Finnish wastewater in 2021-2022.
Viivi HeljankoOlga TyniVenla JohanssonJussa-Pekka VirtanenKati RäisänenKirsi-Maarit LehtoAnssi LipponenSami OikarinenTarja Pitkänennull nullAnnamari HeikinheimoPublished in: Antimicrobial resistance and infection control (2024)
Our study highlights the presence of clinically relevant strains of CP E. coli and K. pneumoniae in community wastewater. The results indicate that wastewater surveillance could serve as a monitoring tool for CP Enterobacterales. However, the specificity and sensitivity of the methods should be improved, and technologies, like advanced sequencing methods, should be utilized to distinguish data with public health relevance, harness the full potential of wastewater surveillance, and implement the data in public health surveillance.
Keyphrases
- public health
- klebsiella pneumoniae
- escherichia coli
- wastewater treatment
- multidrug resistant
- anaerobic digestion
- electronic health record
- global health
- mental health
- healthcare
- big data
- biofilm formation
- acinetobacter baumannii
- risk assessment
- gram negative
- staphylococcus aureus
- machine learning
- cystic fibrosis
- drug resistant
- climate change
- candida albicans
- deep learning