Transdifferentiation of Human Umbilical Cord-Derived Mesenchymal Stem Cells in Dopaminergic Neurons in a Three-Dimensional Culture.

Ardashir Moayeri Mahmoudreza Hadjighassem Hatef Ghasemi Hamidabadi Maryam Nazm Bojnordi Ali Niapour Azim Hedayatpour Marzieh Darvishi Fatemeh Heidari Maryam Soleimani Leila Elyasi

Published in: Basic and clinical neuroscience (2022)

Overall, the results of this study suggest that HUC-MSCs can successfully differentiate toward dopaminergic neuron-like cells on Matrigel, having great potential for the treatment of dopaminergic neuron-related diseases.

Keyphrases

umbilical cord
mesenchymal stem cells
endothelial cells
spinal cord
bone marrow
pluripotent stem cells