Association Between Child Sugary Drink Consumption and Serum Lipid Levels in Electronic Health Records.
Ankitha IyerFang-Chi HsuAlex BonnecazeJoseph A SkeltonDeepak PalakshappaKristina H LewisPublished in: Clinical pediatrics (2023)
Sugar-sweetened beverage (SSB) and fruit juice (FJ) consumption may promote lipid abnormalities in childhood. We examined the association between SSB/FJ intake and lipid levels using electronic health record data for 2816 adolescents. Multivariable logistic regression models treated clinical cutpoints for abnormal lipid levels (triglycerides [TG], high-density lipoprotein (HDL), low-density lipoprotein [LDL], and total cholesterol) as dependent variables. In models not adjusted for adiposity, elevated SSB and FJ consumption was associated with increased odds of having abnormally high TG (SSB: odds ratio [OR] = 1.28 (95% confidence interval [CI] = [1.07-1.52], P = .007); FJ: 1.35 ([1.09-1.69], P = .007)) and abnormally low HDL (SSB: 1.47 ([1.17-1.86], P = .001); FJ: 1.35 ([1.02-1.78], P = .03)). Adjusting for adiposity, a likely mediator of the relationship, attenuated these associations. These findings support the need for identifying unhealthy beverage consumption habits during childhood health care visits as a modifiable behavior associated with cardiometabolic risk.
Keyphrases
- electronic health record
- low density lipoprotein
- high density
- clinical decision support
- healthcare
- adverse drug
- fatty acid
- insulin resistance
- young adults
- mental health
- metabolic syndrome
- early life
- body mass index
- type diabetes
- childhood cancer
- machine learning
- skeletal muscle
- big data
- artificial intelligence
- newly diagnosed