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Association between fatty liver index and controlled attenuation parameters as markers of metabolic dysfunction-associated fatty liver disease and bone mineral density: observational and two-sample Mendelian randomization studies.

Lin ZengYan LiChang HongJiaren WangHongbo ZhuQimei LiHao CuiPengcheng MaRuining LiJingzhe HeHong ZhuLi LiuLushan Xiao
Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2024)
No causal effect of MAFLD and hepatic steatosis on BMD was observed in this study, while some metabolic factors were correlated with BMD. This has important implications for understanding the relationship between fatty liver disease and BMD, which may help direct the clinical management of MAFLD patients with osteoporosis.
Keyphrases
  • bone mineral density
  • postmenopausal women
  • body composition
  • fatty acid
  • oxidative stress