Accuracy of novel antigen rapid diagnostics for SARS-CoV-2: A living systematic review and meta-analysis.

Lukas E Brümmer Stephan Katzenschlager Mary Gaeddert Christian Erdmann Stephani Schmitz Marc Bota Maurizio Grilli Jan LarmannMarkus A WeigandNira R Pollock Aurélien Mace Sergio CarmonaStefano OngarelloJilian A Sacks Claudia M Denkinger

Published in: PLoS medicine (2021)

In this study we found that Ag-RDTs detect the vast majority of SARS-CoV-2-infected persons within the first week of symptom onset and those with high viral load. Thus, they can have high utility for diagnostic purposes in the early phase of disease, making them a valuable tool to fight the spread of SARS-CoV-2. Standardization in conduct and reporting of clinical accuracy studies would improve comparability and use of data.

Keyphrases

sars cov
respiratory syndrome coronavirus
randomized controlled trial
adverse drug
highly efficient
data analysis
deep learning
drug induced
placebo controlled