Combinatorial expression of microtubule-associated EB1 and ATIP3 biomarkers improves breast cancer prognosis.

Sylvie Rodrigues-FerreiraAnne NehligClarisse MonchecourtSarah NasrLaetitia FuhrmannMagali Lacroix-TrikiIngrid GarberisVéronique ScottSuzette DelalogeBarbara PistilliPhilippe VielhThierry DuboisAnne Vincent-SalomonFabrice AndréClara Nahmias

Published in: Breast cancer research and treatment (2018)

These studies emphasize the importance of studying combinatorial expression of EB1 and ATIP3 genes and proteins rather than each biomarker alone. A population of highly aggressive breast tumors expressing high-EB1/low-ATIP3 may be considered for the development of new molecular therapies.

Keyphrases

poor prognosis
binding protein
genome wide
long non coding rna
gene expression
dna methylation
single molecule
case control
genome wide analysis