Prognostic value of partial EMT-related genes in head and neck squamous cell carcinoma by a bioinformatic analysis.

Satoru KisodaWenhua ShaoNatsumi FujiwaraYasuhiro MouriTakaaki TsunematsuShengjian JinRieko ArakakiNaozumi IshimaruYasusei Kudo

Published in: Oral diseases (2020)

Our findings suggest that p-EMT program may be involved in poor prognosis of HNSCC. SERPINE1, ITGA5, TGFBI, P4HA2, CDH13, and LAMC2 can be used for a prognostic marker. Moreover, HNSCC cells with p-EMT phenotype can be a useful model for investigating a nature of p-EMT.

Keyphrases

poor prognosis
epithelial mesenchymal transition
long non coding rna
induced apoptosis
signaling pathway
cell cycle arrest
oxidative stress
cell death
pi k akt