Not enough SPIRIT shown in the registration and reporting of orthodontic trial protocols.

Iro EleftheriadiThomais IoannouViktoria KatechiJadbinder SeehraNikolaos Pandis

Published in: European journal of orthodontics (2022)

There is a general lack of awareness of the importance and relevance of the SPIRIT statement. Registration of orthodontic trial protocols has apparently improved; however, 75.5% SPIRIT statement items were not reported in either study time period. The registration and reporting of orthodontic trial protocols should be advocated to circumvent issues relating to selective reporting and outcome reporting bias.

Keyphrases

adverse drug
phase iii
study protocol
phase ii
clinical trial
oral health
randomized controlled trial
emergency department
open label
drug induced