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Effects of 1-kestose on microbiome changes caused by vonoprazan: a randomized, double-blind, placebo-controlled pilot study.

Satoshi FuruneTakahiro SuzukiTakashi HondaKenta YamamotoKazuhiro FurukawaMasanao NakamuraMasatoshi IshigamiFumie KinoshitaYoshihiro KadotaTakumi TochioYoshiharu ShimomuraYoshiki HirookaMitsuhiro FujishiroHiroki Kawashima
Published in: Journal of gastroenterology and hepatology (2023)
The potassium-competitive acid blocker caused dysbiosis in the placebo group; this effect was prevented by 1-kestose. Thus, 1-kestose may be useful in dysbiosis treatment.
Keyphrases
  • placebo controlled
  • double blind
  • phase iii
  • clinical trial
  • study protocol
  • phase ii
  • phase ii study
  • helicobacter pylori
  • randomized controlled trial
  • angiotensin ii
  • angiotensin converting enzyme
  • smoking cessation