Remote blast-related mild traumatic brain injury is associated with differential expression of exosomal microRNAs identified in neurodegenerative and immunological processes.
Christina DevotoVivian A GuedesChen LaiJacqueline J LeeteSara MithaniKatie EdwardsRany VornBao-Xi QuElisabeth A WildeWilliam C WalkerRamon Diaz-ArrastiaJ Kent WernerKimbra KenneyJessica M GillPublished in: Brain injury (2022)
Our findings suggest that chronic neurobehavioral symptoms after blast TBI may pathomechanistically relate to dysregulated cellular pathways involved with neurodegeneration, inflammation, and central hormonal regulation.