Cyclooxygenase-2 expression is positively associated with lymph node metastasis in nasopharyngeal carcinoma.
Gui YangQiaoling DengWei FanZheng ZhangPeipei XuShihui TangPing WangJun'e WangMing-Xia YuPublished in: PloS one (2017)
The results suggest that expression of COX-2 is associated with lymph node metastasis and disease progression in NPC, indicating a potential role in evaluation of prognosis and in treatment decisions. COX-2 inhibitors have potential in the treatment of NPC that should be further investigated.