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Safety of ibogaine administration in detoxification of opioid-dependent individuals: a descriptive open-label observational study.

Thomas KnuijverArnt F A SchellekensMaarten BelgersRogier DondersToon van OosterenCornelis KramersRobbert Verkes
Published in: Addiction (Abingdon, England) (2021)
This open-label observational study found that ibogaine treatment of patients with opioid use disorder can induce a clinically relevant but reversible QTc prolongation, bradycardia, and severe ataxia.
Keyphrases
  • open label
  • clinical trial
  • phase ii
  • early onset
  • phase iii
  • phase ii study
  • chronic pain
  • pain management
  • drug induced
  • cross sectional
  • squamous cell carcinoma
  • radiation therapy
  • rectal cancer
  • placebo controlled