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Temporal Heterogeneity of HER2 Expression and Spatial Heterogeneity of 18 F-FDG Uptake Predicts Treatment Outcome of Pyrotinib in Patients with HER2-Positive Metastatic Breast Cancer.

Chengcheng GongCheng LiuZhonghua TaoJian ZhangLeiping WangJun CaoYannan ZhaoYizhao XieXichun HuZhongyi YangBi-Yun Wang
Published in: Cancers (2022)
F-FDG uptake could predict the treatment outcome of pyrotinib in patients with HER2-positive MBC, which provide practically applicable methods to assess tumor heterogeneity and guidance for treatment decisions.
Keyphrases
  • metastatic breast cancer
  • single cell
  • pet ct
  • pet imaging
  • positron emission tomography
  • poor prognosis
  • computed tomography
  • binding protein
  • combination therapy
  • replacement therapy
  • smoking cessation