Reliable detection of generalized convulsive seizures using an off-the-shelf digital watch: A multisite phase 2 study.
Yash Shashank VakilnaXiaojin LiJaison S HampsonYan HuangJohn C MosherYuri DabaghianXi LuoBlanca TalaveraSandipan PatiMasel ToddRyan HaysCharles Akos SzaboGuo-Qiang ZhangSamden D LhatooPublished in: Epilepsia (2024)
Commercially available wearable digital watches that reliably detect GCS, with minimum false alarm rates, may overcome usage adoption and other limitations of custom-built devices. Contingent on the outcomes of a prospective phase 3 study, such devices have the potential to provide non-EEG-based seizure surveillance and forecasting in the clinical setting.
Keyphrases
- open label
- public health
- placebo controlled
- double blind
- temporal lobe epilepsy
- functional connectivity
- working memory
- loop mediated isothermal amplification
- resting state
- heart rate
- electronic health record
- label free
- clinical trial
- human health
- randomized controlled trial
- risk assessment
- skeletal muscle
- weight loss