Cell-type dependent regulation of pluripotency and chromatin remodeling genes by hydralazine.

Alain Aguirre-VázquezFabiola Castorena-TorresBeatriz Silva-RamírezKatia Peñuelas-UrquidesMaría Elena Camacho-MollLuis A Salazar-OlivoIván VelascoMario Bermudez de Leon

Published in: Stem cell research & therapy (2023)

Our data provide evidence that HYD regulates the expression of OCT4 and NANOG pluripotency genes as well as ARID1A and ARID2 genes, two members of the SWI/SNF chromatin remodeling complex family, in normal human dermal fibroblasts.

Keyphrases

genome wide
genome wide identification
gene expression
bioinformatics analysis
dna damage
transcription factor
dna methylation
endothelial cells
poor prognosis
genome wide analysis
optical coherence tomography
extracellular matrix
induced pluripotent stem cells
deep learning
binding protein