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Unsaturated Fatty Acid-Induced Conformational Transitions and Aggregation of the Repeat Domain of Tau.

Carlo Giorgio BarracchiaRoberto TiraFrancesca ParoliniFrancesca MunariLuigi BubaccoGeorgios A SpyrouliasMariapina D'OnofrioMichael Assfalg
Published in: Molecules (Basel, Switzerland) (2020)
This study describes the reciprocal influence that Tau4RD and fatty acids exert on their conformational states, contributing to our understanding of fundamental aspects of Tau/lipid co-assembly.
Keyphrases
  • fatty acid
  • cerebrospinal fluid
  • molecular dynamics
  • molecular dynamics simulations
  • single molecule
  • high glucose
  • diabetic rats
  • endothelial cells