Brain Microglial Activation Increased in Glucocerebrosidase (GBA) Mutation Carriers without Parkinson's disease.
Stephen MullinMorten Gersel StokholmDerralyn HughesAtul MehtaPeter ParboRainer HinzNicola PaveseDavid J BrooksAnthony H V SchapiraPublished in: Movement disorders : official journal of the Movement Disorder Society (2020)
In vivo 11 C-(R)-PK11195 PET imaging detects neuroinflammation in brain regions susceptible to Lewy pathology in glucocerebrosidase gene mutation carriers without Parkinson's. © 2020 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Keyphrases
- pet imaging
- resting state
- white matter
- cerebral ischemia
- lipopolysaccharide induced
- lps induced
- functional connectivity
- inflammatory response
- traumatic brain injury
- positron emission tomography
- parkinson disease
- neuropathic pain
- computed tomography
- randomized controlled trial
- multiple sclerosis
- spinal cord injury
- cognitive impairment
- meta analyses