The potential toxic impact of different gadolinium-based contrast agents combined with 7-T MRI on isolated human lymphocytes.

Björn FriebeFrank GodenschwegerMahsa FatahiOliver SpeckDirk RoggenbuckDirk ReinholdAnnika Reddig

Published in: European radiology experimental (2018)

Exposure of lymphocytes to different GBCAs did not reveal significant induction of γH2AX foci, and enhanced cytotoxicity was only observed in lymphocytes treated with the linear GBCAs used in this study, independent of additional 7-T MRI co-exposure.

Keyphrases

contrast enhanced
peripheral blood
magnetic resonance imaging
magnetic resonance
endothelial cells
diffusion weighted imaging
computed tomography
single cell
gene expression
pluripotent stem cells
climate change
dna methylation
human health