Variants at the ASIP locus contribute to coat color darkening in Nellore cattle.
Beatriz B TrigoAdam T H UtsunomiyaAlvaro A A D FortunatoMarco MilanesiRafaela B P TorrecilhaHarrison LambLoan NguyenElizabeth M RossBen HayesRômulo C M PadulaThayla S SussaiLudmilla B ZavarezRafael S CiprianoMaria M T CaminhasFlavia L LopesCassiano PelleTosso LeebDanika BannaschDerek BickhartTimothy P L SmithTad S SonstegardJosé F GarciaYuri Tani UtsunomiyaPublished in: Genetics, selection, evolution : GSE (2021)
Our results indicate that the variant ASIP sequence causes darker coat pigmentation on specific parts of the body, most likely through a decreased expression of ASIP and consequently an increased production of eumelanin.