Zn-ProPhenol catalyzed asymmetric inverse-electron-demand Diels-Alder reaction.

Yu-Hang MiaoYuan-Zhao HuaShi-Kun JiaXiao Xiao Min-Can Wang Guang-Jian Mei

Published in: Chemical communications (Cambridge, England) (2023)

The first Zn-ProPhenol catalyzed asymmetric inverse-electron-demand Diels-Alder reaction has been accomplished. This protocol was carried out by a dual-activation mode under mild conditions, allowing the preparation of various biologically important dihydropyrans in good yields with excellent stereoselectivities.

Keyphrases

electron transfer
room temperature
heavy metals
randomized controlled trial
solid state
electron microscopy
molecularly imprinted
mass spectrometry
high resolution
liquid chromatography