Bovine pestivirus is a new alternative virus for multiple myeloma oncolytic virotherapy.

Valentina MarchicaValentina FranceschiRosanna VescoviniPaola StortiEmanuela VicarioDenise ToscaniAlessia ZorzoliIrma AiroldiBenedetta Dalla PalmaNicoletta CampaniniEugenia MartellaCristina ManciniFederica CostaGaetano DonofrioNicola Giuliani

Published in: Journal of hematology & oncology (2020)

Overall, our data indicate, for the first time, a direct oncolytic effect of the BVDV in human myeloma cells suggesting its possible use as novel alternative anti-myeloma virotherapy strategy.

Keyphrases

multiple myeloma
induced apoptosis
endothelial cells
cell cycle arrest
newly diagnosed
electronic health record
induced pluripotent stem cells
big data
pluripotent stem cells
oxidative stress
signaling pathway
cell death
machine learning
cell proliferation
pi k akt
deep learning
artificial intelligence