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Multimodal longitudinal study of structural brain involvement in amyotrophic lateral sclerosis.

Hannelore K van der BurghHenk-Jan WestenengRenée WalhoutKevin van VeenhuijzenHarold H G TanJil M MeierLeonhard A BakkerJeroen HendrikseMichael A van EsJan Herman VeldinkMartijn P van den HeuvelLeonard H van den Berg
Published in: Neurology (2020)
Heterogeneity of phenotype and C9orf72 genotype relates to distinct patterns of cerebral degeneration. We demonstrate that imaging studies have the potential to monitor disease progression and early intervention may be required to limit cerebral degeneration.
Keyphrases
  • subarachnoid hemorrhage
  • cerebral ischemia
  • randomized controlled trial
  • high resolution
  • resting state
  • white matter
  • pain management
  • case control
  • human health
  • functional connectivity
  • mass spectrometry