Randomized head-to-head comparison of minodronic acid and raloxifene for fracture incidence in postmenopausal Japanese women: the Japanese Osteoporosis Intervention Trial (JOINT)-04.
Yukari UemuraTeruki SoneShiro TanakaTeruhiko MiyazakiMayumi TsukiyamaAkira TaguchiSatoshi SoenSatoshi MoriHiroshi HaginoToshitsugu SugimotoMasao FukunagaHiroaki OhtaToshitaka NakamuraHajime OrimoMasataka Shirakinull nullPublished in: Current medical research and opinion (2020)
Overall, there were no statistical differences in the incidence rates of osteoporotic, vertebral, or major osteoporotic fractures between the two groups. Serious adverse reactions were rare in both groups.
Keyphrases
- bone mineral density
- postmenopausal women
- phase iii
- body composition
- risk factors
- phase ii
- optic nerve
- randomized controlled trial
- open label
- double blind
- clinical trial
- study protocol
- polycystic ovary syndrome
- placebo controlled
- type diabetes
- emergency department
- metabolic syndrome
- pregnancy outcomes
- breast cancer risk
- cervical cancer screening
- adverse drug