Hemostatic profile under fluid resuscitation during rivaroxaban anticoagulation: an in vitro survey.
Tuukka Antero HelinMarleen ZuurveldMikko ManninenJoost C M MeijersRiitta LassilaHerm Jan M BrinkmanPublished in: Transfusion (2018)
In the setting of rivaroxaban anticoagulation and major blood loss, transfusing plasma together with PCC may provide the most effective resuscitation approach with the notion that additional antifibrinolytic drug support (e.g., tranexamic acid) is likely required.