Two children with neuroblastoma underwent tumor resection and postoperative chemotherapy. After treatment, they participated in a clinical trial and received 18 F-MFBG and 18 F-FDG PET/CT examinations. Although similar lesions were found in the 2 examinations, the uptake pattern was different. The lymph nodes and bone lesions had intense 18 F-MFBG activity, whereas 18 F-FDG uptake was not very impressive. The uptake of bone marrow by 18 F-MFBG was significantly stronger than that by 18 F-FDG. This case emphasizes that 18 F-MFBG PET/CT is superior to 18 F-FDG PET/CT in detecting the metastases of neuroblastoma.
Keyphrases
- pet ct
- bone marrow
- clinical trial
- lymph node
- positron emission tomography
- squamous cell carcinoma
- patients undergoing
- small cell lung cancer
- mesenchymal stem cells
- deep learning
- young adults
- bone mineral density
- randomized controlled trial
- machine learning
- open label
- optical coherence tomography
- computed tomography
- early stage
- double blind
- body composition
- neoadjuvant chemotherapy
- phase iii
- clinical evaluation