Blood biomarkers for the diagnosis and differentiation of stroke: A systematic review and meta-analysis.
Shubham MisraJoan MontanerLaura RamiroRohan AroraPumanshi TalwarManabesh NathAmit KumarKameshwar PrasadAwadh K PanditDheeraj MohaniaKameshwar PrasadDeepti VibhaPublished in: International journal of stroke : official journal of the International Stroke Society (2020)
This meta-analysis highlights the potential of brain natriuretic peptide, matrix metalloproteinase-9, D-dimer, and glial fibrillary acidic protein as diagnostic biomarkers for stroke within 24 h. Results of our meta-analysis might serve as a platform for conducting further targeted proteomics studies and phase-III clinical trials.PROSPERO Registration ID: CRD42019139659.
Keyphrases
- systematic review
- phase iii
- clinical trial
- case control
- meta analyses
- atrial fibrillation
- open label
- phase ii
- cerebral ischemia
- mass spectrometry
- randomized controlled trial
- ionic liquid
- risk assessment
- cancer therapy
- neuropathic pain
- resting state
- human health
- small molecule
- binding protein
- protein protein
- multiple sclerosis
- placebo controlled
- subarachnoid hemorrhage
- single cell
- brain injury